BDBM268602 N-(7-(adamantan-1-ylmethoxy)-6-ethyl-[1,2,4]triazolo[4,3-a]-pyridin-3-yl)methanesulfonamide::US9550775, 125
SMILES CCc1cn2c(NS(C)(=O)=O)nnc2cc1OCC12CC3CC(CC(C3)C1)C2
InChI Key InChIKey=ZDVPWQBMSWEBJS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 268602
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]GX-545 from recombinant human NaV1.7 expressed in HEK293 cell membranes coexpressing Nav beta1 subunit after 18 hrs by liquid sci...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
Curated by ChEMBL
Xenon Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 41nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair