BDBM269496 (S)-N-(3-(6-amino-3,3-difluoro-2-(fluoromethyl)-2,3,4,5-tetrahydropyridin-2-yl)-4,5-difluorophenyl)-5-fluoropicolinamide ::US10058540, 12
SMILES NC1=N[C@](CF)(c2cc(NC(=O)c3ccc(F)cn3)cc(F)c2F)C(F)(F)CC1
InChI Key InChIKey=WKYPZLBJTZQTPX-QGZVFWFLSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 269496
Affinity DataKi: 84nM ΔG°: -9.65kcal/molepH: 4.5 T: 2°CAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair