BDBM269884 (1S,2R)N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-1-(2-hydroxyethoxy)-1-(5-methylpyrimidin-2-yl)propane-2-sulfonamide or (1R,2S)N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxypyridin-2-yl)-4H-1,2,4-triazol-3-yl)-1-(2-hydroxyethoxy)-1-(5-methylpyrimidin-2-yl)propane-2-sulfonamide::US10058550, Example 415.0::US10058550, Example 416.0::US10221162, Example 416.0::US9845310, Example 416.0
SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@@H](C)[C@H](OCCO)c2ncc(C)cn2)n1-c1c(OC)cccc1OC
InChI Key InChIKey=UVLJQFUMOVICAW-SBUREZEXSA-N
Data 6 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 269884
Affinity DataEC50: 8.90nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Affinity DataEC50: 0.260nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Affinity DataEC50: 0.260nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Affinity DataEC50: 0.260nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Affinity DataEC50: 8.90nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Affinity DataEC50: 8.90nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair