BDBM270595 US10059695, II-1::US10577352, Compound II-1::benzyl 4-(4-(((8- chloro-4-((3-chloro- 4- fluorophenyl)amino) quinazolin-6- yl)amino)(phenyl) methyl)-1H-1,2,3- triazol-1- yl)piperidine-1- carboxylate

SMILES Fc1ccc(Nc2ncnc3c(Cl)cc(NC(c4cn(nn4)C4CCN(CC4)C(=O)OCc4ccccc4)c4ccccc4)cc23)cc1Cl

InChI Key InChIKey=GGYCDQCSXUHDEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 270595   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270595(US10059695, II-1 | US10577352, Compound II-1 | ben...)
Affinity DataIC50:  8.48E+3nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270595(US10059695, II-1 | US10577352, Compound II-1 | ben...)
Affinity DataIC50:  8.48E+3nMpH: 7.0 T: 2°CAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent