BDBM270599 (S)-N6-((1-(1-(tert- butyl)piperidin-4- yl)-1H-1,2,3-triazol- 4-yl)(4- chlorophenyl) methyl)-N4-(3- chloro-4- fluorophenyl) quinazoline- 4,6-diamine::US10059695, II-5::US10577352, Compound II-5

SMILES CC(C)(C)N1CCC(CC1)n1cc(nn1)[C@@H](Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1

InChI Key InChIKey=UMZDDZPSFCBSGA-PMERELPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 270599   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270599((S)-N6-((1-(1-(tert- butyl)piperidin-4- yl)-1H-1,2...)
Affinity DataIC50:  72nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270599((S)-N6-((1-(1-(tert- butyl)piperidin-4- yl)-1H-1,2...)
Affinity DataIC50:  72nMpH: 7.0 T: 2°CAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent