BDBM270601 (S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chlorophenyl)(1- (oxetan-3-yl)-1H- 1,2,3-triazol-4- yl)methyl) quinazoline- 4,6-diamine::US10059695, II-7::US10577352, Compound II-7

SMILES Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl

InChI Key InChIKey=TUXTUSCLXYRBTM-VWLOTQADSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 270601   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270601((S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chloroph...)
Affinity DataIC50:  284nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM270601((S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chloroph...)
Affinity DataIC50:  284nMpH: 7.0 T: 2°CAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent