BDBM272065 (S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl- l,4,5,6-tetrahydrocyclopenta[c]pyrazole-5- carboxamide::US10065948, 1::US10457675, Example 30

SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccccc1)C(=O)NO

InChI Key InChIKey=KKIYRHFRGICIJN-FQEVSTJZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 272065   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272065((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl...)
Affinity DataIC50:  28nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272065((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272065((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl...)
Affinity DataIC50:  28nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent