BDBM272130 (R)-5-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)- N-hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-5- carboxamide::US10065948, 66::US10457675, Example 66

SMILES Cc1c(F)cccc1[C@]1(Cc2nc(sc2C1)-c1ccc(F)cc1)C(=O)NO

InChI Key InChIKey=XESWLHUWEZFSSE-HXUWFJFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272130   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272130((R)-5-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)...)
Affinity DataIC50:  81nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272130((R)-5-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)...)
Affinity DataIC50:  81nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent