BDBM272137 (S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o- tolyl)-5,6-dihydro-4H-cyclopenta[d]thiazole-6- carboxamide::US10065948, 73::US10457675, Example 73

SMILES Cc1ccccc1-c1nc2CC[C@](C(=O)NO)(c2s1)c1cccc(F)c1C

InChI Key InChIKey=BCXSCVXYWCEYON-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272137   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272137((S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o- to...)
Affinity DataIC50:  143nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272137((S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o- to...)
Affinity DataIC50:  143nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent