BDBM272157 (S)-1-Benzyl-5-(3-fluoro-2-methylphenyl)-N-hydroxy- 1,4,5,6-tetrahydrocyclopenta[c]pyrazole-5- carboxamide::US10065948, 92::US10457675, Example 92

SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(Cc3ccccc3)c2C1)C(=O)NO

InChI Key InChIKey=FLMXRQPTJQVIKH-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272157   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272157((S)-1-Benzyl-5-(3-fluoro-2-methylphenyl)-N-hydroxy...)
Affinity DataIC50:  48nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272157((S)-1-Benzyl-5-(3-fluoro-2-methylphenyl)-N-hydroxy...)
Affinity DataIC50:  48nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent