BDBM272158 (R)-1-Benzyl-4-(3-fluoro-2-methylphenyl)-N-hydroxy- 1,4,5,6-tetrahydrocyclopenta[c]pyrazole-4- carboxamide::US10065948, 93::US10457675, Example 93

SMILES Cc1c(F)cccc1[C@@]1(CCc2c1cnn2Cc1ccccc1)C(=O)NO

InChI Key InChIKey=UYVIIAWTLQUSMW-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272158   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272158((R)-1-Benzyl-4-(3-fluoro-2-methylphenyl)-N-hydroxy...)
Affinity DataIC50:  27nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM272158((R)-1-Benzyl-4-(3-fluoro-2-methylphenyl)-N-hydroxy...)
Affinity DataIC50:  27nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent