BDBM272991 (S)-2-((1-(5-(1H-1,2,4- triazol-5-yl)pyridin-2- yl)-7,8,9,10-tetrahydro- 6-oxa-2,10a- diazacycloocta[cd]inden-4- yl)oxy)propanamide::US10065970, Example 296::US10435414, Example 296

SMILES C[C@H](Oc1cc2OCCCCn3c(nc(c1)c23)-c1ccc(cn1)-c1ncn[nH]1)C(N)=O

InChI Key InChIKey=SFIUNLKXBNSMLB-LBPRGKRZSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272991   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM272991((S)-2-((1-(5-(1H-1,2,4- triazol-5-yl)pyridin-2- yl...)
Affinity DataKi: <0.0200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM272991((S)-2-((1-(5-(1H-1,2,4- triazol-5-yl)pyridin-2- yl...)
Affinity DataKi: <0.0200nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent