BDBM274689 N-(6-(1-((5-tert-butyl-1H-pyrazol- 3-yl)methyl)-4-(4-fluorophenyl-1H- imidazol-5-yl)imidazo[1,2-b] pyridazin-2-yl)-2-fluoroiso- nicotinamide::US9556179, Compound 264

SMILES CC(C)(C)c1cc(Cn2cnc(c2-c2ccc3nc(NC(=O)c4ccnc(F)c4)cn3n2)-c2ccc(F)cc2)n[nH]1

InChI Key InChIKey=FXJSILDAOLMLEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274689   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274689(N-(6-(1-((5-tert-butyl-1H-pyrazol- 3-yl)methyl)-4-...)
Affinity DataIC50:  41.5nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274689(N-(6-(1-((5-tert-butyl-1H-pyrazol- 3-yl)methyl)-4-...)
Affinity DataIC50:  156nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent