BDBM27604 2-{[4-(4-tert-butyl-2-chlorophenyl)-5-methyl-1H-pyrazol-3-yl]oxy}-N-[2-chloro-4-(4-hydroxy-3,3-dimethylbut-1-yn-1-yl)phenyl]acetamide::pyrazolyl compound, 42
SMILES Cc1[nH]nc(OCC(=O)Nc2ccc(cc2Cl)C#CC(C)(C)CO)c1-c1ccc(cc1Cl)C(C)(C)C
InChI Key InChIKey=IVPUMMMSBHDOHK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 27604
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)
Boehringer Ingelheim (Canada)
Affinity DataIC50: 24nM EC50: 177nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation prox imity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value repres...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Boehringer Ingelheim (Canada)
Boehringer Ingelheim (Canada)
Affinity DataIC50: >3.30E+3nM EC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair