BDBM276802 (R)-5-(5-(((S)-5-chloro-2,3-dihydro-1H-inden-1-yl)amino)-2-fluorophenyl)-3-imino-2,5-dimethyl-1,2,4-thiadiazinane 1,1-dioxide::US10071998, Example 17
SMILES CN1C(=N)N[C@@](C)(CS1(=O)=O)c1cc(N[C@H]2CCc3cc(Cl)ccc23)ccc1F
InChI Key InChIKey=DLNOZHRWIDUXQZ-ICSRJNTNSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 276802
Affinity DataKi: 10.2nMpH: 5.0Assay Description:The following reagents were used in this assay. Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE-1...More data for this Ligand-Target Pair
Affinity DataKi: 16.6nMpH: 5.0Assay Description:Inhibitor IC50s, at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEV...More data for this Ligand-Target Pair