BDBM277089 4-(4-chloro-2- fluorophenyl)-7-[(1- methyl-1H-pyrazol-5- yl)methyl]-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 1-8

SMILES Cn1nccc1CN1CCc2c(C1)nc(cc2-c1ccc(Cl)cc1F)C(N)=O

InChI Key InChIKey=XMBIDPMVZGDWBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277089   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277089(4-(4-chloro-2- fluorophenyl)-7-[(1- methyl-1H-pyra...)
Affinity DataIC50:  8.70E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent