BDBM277101 (S) or (R)-4-(4-chloro-2- fluorophenyl)-7-(((S) or (R)-2,2- dimethyltetrahydro-2H- pyran-4-yl)methyl)-8- methyl-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 1-18

SMILES CC1N(CC2CCOC(C)(C)C2)CCc2c1nc(cc2-c1ccc(F)cc1F)C(N)=O

InChI Key InChIKey=DVMUCHAWUJZPAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277101   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277101((S) or (R)-4-(4-chloro-2- fluorophenyl)-7-(((S) or...)
Affinity DataIC50:  1.23E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent