BDBM277114 4-(2,4-difluorophenyl)-7-[(4-methyl-1,2,5- oxadiazol-3-yl)methyl]-5,6,7,8-tetrahydro- 1,7-naphthyridine-2-carboxamide::US10072003, Example 2-7

SMILES Cc1nonc1CN1CCc2c(C1)nc(cc2-c1ccc(F)cc1F)C(N)=O

InChI Key InChIKey=MIPDJWUCMMLVMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277114   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277114(4-(2,4-difluorophenyl)-7-[(4-methyl-1,2,5- oxadiaz...)
Affinity DataIC50:  7.60E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent