BDBM277116 7-[(2-cyclopropylpyridin-4-yl)methyl]-4-[1- (difluoromethyl)-1H-pyrazol-4-yl]-5,6,7,8- tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 2-9

SMILES NC(=O)c1cc(-c2cnn(c2)C(F)F)c2CCN(Cc3ccnc(c3)C3CC3)Cc2n1

InChI Key InChIKey=ZVLAUIGEFCGBRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277116   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277116(7-[(2-cyclopropylpyridin-4-yl)methyl]-4-[1- (diflu...)
Affinity DataIC50:  1.08E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent