BDBM277118 4-(2-chloro-4-fluorophenyl)-7-{[2- (difluoromethoxy)pyridin-4-yl]methyl}- 5,6,7,8-tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 2-11

SMILES NC(=O)c1cc(c2CCN(Cc3ccnc(OC(F)F)c3)Cc2n1)-c1ccc(F)cc1Cl

InChI Key InChIKey=VTIVDVBGFHFMJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277118   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277118(4-(2-chloro-4-fluorophenyl)-7-{[2- (difluoromethox...)
Affinity DataIC50:  1.04E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent