BDBM277133 4-(2,4-difluorophenyl)-7-[(4- methylisoxazol-3-yl)methyl]-5,6,7,8- tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 2-26

SMILES Cc1conc1CN1CCc2c(C1)nc(cc2-c1ccc(F)cc1F)C(N)=O

InChI Key InChIKey=CVGZMBCTEWTMPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277133   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277133(4-(2,4-difluorophenyl)-7-[(4- methylisoxazol-3-yl)...)
Affinity DataIC50:  1.31E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent