BDBM277137 US10072003, Example 3-2A::US10072003, Example 3-2B

SMILES COc1cc(ccn1)C(N1CCc2c(C1)nc(cc2-c1cnn(C)c1)C(N)=O)C(F)(F)F

InChI Key InChIKey=MZWONZQRCSLBJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 277137   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277137(US10072003, Example 3-2A | US10072003, Example 3-2...)
Affinity DataIC50:  1.14E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277137(US10072003, Example 3-2A | US10072003, Example 3-2...)
Affinity DataIC50:  9.60E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent