BDBM277149 (S) or (R)-4-(3- fluoropiperidin-1-yl)-7-((2- (trifluoromethyl)pyridin-4- yl)methyl)-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 5-6A::US10072003, Example 5-6B
SMILES NC(=O)c1cc(N2CCCC(F)C2)c2CCN(Cc3ccnc(c3)C(F)(F)F)Cc2n1
InChI Key InChIKey=XKQQXSKTCUSKLA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 277149
Affinity DataIC50: 1.73E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair