BDBM277149 (S) or (R)-4-(3- fluoropiperidin-1-yl)-7-((2- (trifluoromethyl)pyridin-4- yl)methyl)-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 5-6A::US10072003, Example 5-6B

SMILES NC(=O)c1cc(N2CCCC(F)C2)c2CCN(Cc3ccnc(c3)C(F)(F)F)Cc2n1

InChI Key InChIKey=XKQQXSKTCUSKLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 277149   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277149((S) or (R)-4-(3- fluoropiperidin-1-yl)-7-((2- (tri...)
Affinity DataIC50:  1.73E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277149((S) or (R)-4-(3- fluoropiperidin-1-yl)-7-((2- (tri...)
Affinity DataIC50:  2.14E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent