BDBM277164 US10072003, Example 8-1A::US10072003, Example 8-1B::US10072003, Example 8-3A::US10072003, Example 8-3B

SMILES NC(=O)c1cc(c2CCN(CC(O)c3ccccc3)Cc2n1)-c1ccc(F)cc1F

InChI Key InChIKey=WZNWMIXKKLRVEL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 277164   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277164(US10072003, Example 8-1A | US10072003, Example 8-1...)
Affinity DataIC50:  1.85E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277164(US10072003, Example 8-1A | US10072003, Example 8-1...)
Affinity DataIC50:  1.27E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277164(US10072003, Example 8-1A | US10072003, Example 8-1...)
Affinity DataIC50:  1.85E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277164(US10072003, Example 8-1A | US10072003, Example 8-1...)
Affinity DataIC50:  1.27E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent