BDBM277189 4-(4-chloro-2,6-difluorophenyl)-7-{[2- (trifluoromethyl)pyrimidin-4-yl]methyl}- 5,6,7,8-tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 11-9

SMILES NC(=O)c1cc(c2CCN(Cc3ccnc(n3)C(F)(F)F)Cc2n1)-c1c(F)cc(Cl)cc1F

InChI Key InChIKey=LTFOPYLGWHOPII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277189   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM277189(4-(4-chloro-2,6-difluorophenyl)-7-{[2- (trifluorom...)
Affinity DataIC50:  6.50E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent