BDBM277698 N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxyethoxy)ethoxy)-5-methoxyphenyl)amino)-pyridin-4-yl)oxy)naphthalen-1-yl)ureido)-5-(tert-butyl)-2-methoxyphenyl)methanesulfonamide::US10072034, Example 23

SMILES COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OCCOCCOCc2nnn[nH]2)c1

InChI Key InChIKey=BTPIXSACPPUAOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277698   

TargetInterleukin-8(Homo sapiens (Human))
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US Patent
LigandPNGBDBM277698(N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxy...)
Affinity DataIC50:  29.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent