BDBM278446 US10040788, Example 28(b)

SMILES CCO[C@H](C(=O)Nc1nnc(N[C@H]2CCN(C2)c2cccnn2)s1)c1ccc(OC)cc1

InChI Key InChIKey=PRHCXSNDPXZCNA-YJBOKZPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 278446   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM278446(US10040788, Example 28(b))
Affinity DataIC50:  84.8nMpH: 7.8Assay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent