BDBM278941 4-{8-amino-3- [(6R,8aS)-6-methyl-3- oxohexahydro[1,3] oxazolo[3,4-a]pyridin-6- yl]imidazo[1,5- a]pyrazin-1-yl}-3- ethoxy-5-fluoro-N-[4- (trifluoromethyl) pyridin-2-yl] benzamide::US10040805, Example 11
SMILES CCOc1cc(cc(F)c1-c1nc(n2ccnc(N)c12)[C@]1(C)CC[C@H]2COC(=O)N2C1)C(=O)Nc1cc(ccn1)C(F)(F)F
InChI Key InChIKey=KSGNUSPSHBOAMI-YMGMXPECSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278941
Affinity DataIC50: 0.590nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair