BDBM278970 US10040815, Example 42::US10618929, Example 42::[(1S)-1-[(2S,4R,5R)-5-(5-Amino-2,7-dioxo-6H-thiazolo[4,5-d]pyrimidin-3-yl)-4-hydroxy-tetrahydrofuran-2-yl]propyl] 2-methylpropanoate

SMILES CC[C@H](OC(=O)C(C)C)[C@@H]1C[C@@H](O)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 278970   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM278970(US10040815, Example 42 | US10618929, Example 42 | ...)
Affinity DataEC50:  5.10E+4nMAssay Description:A stable HEK293-Blue-hTLR-7 cell line was purchased from InvivoGen (Cat. #: hkb-ht1r7, San Diego, Calif., USA). These cells were designed for studyin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM278970(US10040815, Example 42 | US10618929, Example 42 | ...)
Affinity DataEC50:  5.10E+4nMAssay Description:A stable HEK293-Blue-hTLR-7 cell line was purchased from InvivoGen (Cat.#: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent