BDBM279103 3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-triazol-3-yl)methyl]-5-(2-propoxy-3-pyridyl)pyrazolo[4,3-b]pyridin-7-amine,enantiomer 2::US10034861, Example 134::US10512632, Example 134::US10766893, Example S134::US10806718, Example 134::US11491140, Example 134::US11634416, Example 134

SMILES CCCOc1ncccc1-c1cc(NCc2ncn(C)n2)c2n(nc(C)c2n1)C(C)CC

InChI Key InChIKey=SXNFSKBWTTYFLI-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 279103   

LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.960nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  1.5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  1.5nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.960nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.120nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  1.5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.960nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.120nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  1.5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.960nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.120nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  1.5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.960nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.120nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  1.5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.960nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.120nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM279103(3-methyl-1-[1-methylpropyl]-N-[(1-methyl-1,2,4-tri...)
Affinity DataIC50:  0.120nMpH: 7.6 T: 2°CAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent