BDBM279845 US10028934, Ref. Compound

SMILES CN(C)c1ccc(cc1)C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12

InChI Key InChIKey=IZQJMIVZMPULKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 279845   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 279845BDBM279845(US10028934, Ref. Compound)
Affinity DataIC50: 3.18E+3nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Nerviano Medical Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 279845BDBM279845(US10028934, Ref. Compound)
Affinity DataIC50: 1.00E+4nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent