BDBM28137 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(3-chlorobenzene)sulfonyl]-2-fluoroacetate::tetrahydro-carbazole, (+/-)17

SMILES [H][C@]1(CCc2c(C1)[nH]c1ccc(Cl)cc21)[C@@](F)(C(=O)OC)S(=O)(=O)c1cccc(Cl)c1

InChI Key InChIKey=KPQLWJWAGXJIST-GTJPDFRWSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28137   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28137(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  31nM EC50:  1.81E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28137(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  100nM EC50:  2.17E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed