BDBM28145 methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-7,12-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9,11-tetraen-4-yl]-2-fluoroacetate::tetrahydro-cyclopenta[b]indole, (+/-)25

SMILES [H][C@@]1(Cc2[nH]c3ccc(Cl)nc3c2C1)[C@@](F)(C(=O)OC)S(=O)(=O)c1ccccc1

InChI Key InChIKey=QUJZEJMHCCGRNR-WYRIXSBYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28145   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28145(methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-...)
Affinity DataIC50:  400nM EC50:  370nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28145(methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-...)
Affinity DataIC50:  2.58E+3nM EC50:  4.23E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed