BDBM281760 4-(2-acryloyl-1,2,3,4- tetrahydroisoquinolin- 5-yl)-3-fluoro-N7,N7- dimethyl-9H-carbazole- 1,7-dicarboxamide::US10023534, Example 28
SMILES CN(C)C(=O)c1ccc2c(c1)[nH]c1c(cc(F)c(-c3cccc4CN(CCc34)C(=O)C=C)c21)C(N)=O
InChI Key InChIKey=VGYWWAHJSISJEH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 281760
Affinity DataIC50: 0.170nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair