BDBM28222 7-{5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-3-yl}-1,6-naphthyridin-8-ol::oxadiazole substituted naphthyridine, 10c

SMILES Oc1c(ncc2cccnc12)-c1noc(Cc2ccc(F)cc2)n1

InChI Key InChIKey=JQTFAOQFMPMHDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28222   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28222(7-{5-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  130nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed