BDBM28267 1,3,4-oxadiazole substituted naphthyridine, 35::7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2-yl}-5-(pyridin-4-yl)-1,6-naphthyridin-8-ol

SMILES Oc1c(nc(-c2ccncc2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1

InChI Key InChIKey=IUMHLAGWWNQZDQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28267   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28267(1,3,4-oxadiazole substituted naphthyridine, 35 | 7...)
Affinity DataIC50:  8nMAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed