BDBM282781 (S)-2-(4-oxo-1-phenyl-1,3,8- triazaspiro[4.5]decan-8-yl)-6-((2- oxopyrrolidin-3- yl)amino)pyrimidine-4- carboxamide::US11180502, Compound 11::US9884865, Compound 11

SMILES NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=VIKKCHAOQKSODM-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 282781   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM282781((S)-2-(4-oxo-1-phenyl-1,3,8- triazaspiro[4.5]decan...)
Affinity DataIC50: >2.00E+4nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM282781((S)-2-(4-oxo-1-phenyl-1,3,8- triazaspiro[4.5]decan...)
Affinity DataIC50: >2.00E+4nMpH: 7.3Assay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent