BDBM282821 (R)-6-(4-(4-fluorophenyl)-1-(4,4,4-trifluoro-1- hydroxybutan-2-yl)-1H-imidazol-5-yl)imidazo[1,2- b]pyridazine-3-carbonitrile::US10287295, Example 28'::US11352360, Example 28'::US9884868, Example 28'
SMILES OC[C@@H](CC(F)(F)F)n1cnc(c1-c1ccc2ncc(C#N)n2n1)-c1ccc(F)cc1
InChI Key InChIKey=PJHMWSSMEQZEOI-CQSZACIVSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 282821
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair