BDBM28286 1,3,4-oxadiazole substituted naphthyridine, 54::7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2-yl}-5-(2-methanesulfonylphenyl)-1,6-naphthyridin-8-ol

SMILES CS(=O)(=O)c1ccccc1-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12

InChI Key InChIKey=FNQKXILIIVSGEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28286   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gsk

LigandPNGBDBM28286(1,3,4-oxadiazole substituted naphthyridine, 54 | 7...)
Affinity DataIC50:  11nMAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed