BDBM283758 N-(4-(azetidin-3-ylidenemethyl)-3,5-difluorophenyl)-3-ethyl-4-methyl-1H-pyrazole-5-carboxamide::US10023559, Example 83

SMILES CCc1n[nH]c(C(=O)Nc2cc(F)c(C=C3CNC3)c(F)c2)c1C

InChI Key InChIKey=UXYBPJXHXJWOHR-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283758   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM283758(N-(4-(azetidin-3-ylidenemethyl)-3,5-difluorophenyl...)
Affinity DataKi:  0.900nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM283758(N-(4-(azetidin-3-ylidenemethyl)-3,5-difluorophenyl...)
Affinity DatapH: 7.4Assay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent