BDBM285689 US10077273, Compound HK-X3::US10934305, Compound HK-X3
SMILES CC(C)C1(c2c(C)n[nH]c2OC(N)=C1C#N)c1cc(CO)cc(c1)-c1cccc(CC(N)=O)c1
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 285689
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 7.80nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 16.9nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 7.80nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 16.9nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair