BDBM285690 6-amino-4-(3-bromo-5-(trifluoromethyl)phenyl)-4-isopropyl-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile ::US10077273, Compound a::US10934305, Compound a
SMILES CC(C)C1(c2c(C)n[nH]c2OC(N)=C1C#N)c1cc(Br)cc(c1)C(F)(F)F
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 285690
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 42nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees of Princeton University
US Patent
The Trustees of Princeton University
US Patent
Affinity DataIC50: 42nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair