BDBM287588 US10420768, Compound C-4::US11752155, Compound C-4A'::US9567341, Compound C-4::US9968610, Compound C-4
SMILES Cc1ccc(nc1)C(F)(F)CN1CCC(CC1)Nc1ncnc2[nH]ccc12
InChI Key InChIKey=RYFZFQVKNZTNST-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 287588
Affinity DataIC50: 35nMpH: 7.35Assay Description:The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37?? C. in a humidified CO2 incubator in the gro...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+7nMpH: 7.4Assay Description:Inhibitory activities of test compounds on 5 major isoforms of CYP P450 were evaluated by using pooled human liver microsome (HLM, purchased from BD ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Rugen Holdings (Cayman)
US Patent
Rugen Holdings (Cayman)
US Patent
Affinity DataIC50: 1.14E+4nMpH: 7.35Assay Description:The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37?? C. in a humidified CO2 incubator in the gro...More data for this Ligand-Target Pair