BDBM288145 (1S,2S)-N7'-(3-chloro-2- fluorobenzyl)-9'-hydroxy-2'- isopropyl-N2,N2-dimethyl- 1',8'-dioxo-1',2',3',8'- tetrahydrospiro[cyclopropane- 1,4'-pyrido[1,2-a]pyrazine]- 2,7'-dicarboxamide hydrochloride::US10087178, Example T13

SMILES CC(C)N1C[C@@]2(C[C@@H]2C(=O)N(C)C)n2cc(C(=O)NCc3cccc(Cl)c3F)c(=O)c(O)c2C1=O

InChI Key InChIKey=AIBFMDDKEKIHSZ-OYLFLEFRSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288145   

TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288145((1S,2S)-N7'-(3-chloro-2- fluorobenzyl)-9'-hydroxy-...)
Affinity DataEC50:  3.40nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent