BDBM288235 5-(7-Chloro-1H-indazol-5-yl)-6-(1,1-difluoroethyl)-2-::US10087185, Example 53

SMILES CC(F)(F)c1ccc2nc(nn2c1-c1cc(Cl)c2[nH]ncc2c1)C(F)(F)F

InChI Key InChIKey=UQZCVPDPZKFDOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288235   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288235(5-(7-Chloro-1H-indazol-5-yl)-6-(1,1-difluoroethyl)...)
Affinity DataIC50:  0.0500nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent