BDBM288239 5-(6-(4-Fluorophenyl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-::US10087185, Example 57

SMILES Cc1cc(cc2CC(=O)Nc12)-c1c(ccc2nc(nn12)C(F)(F)F)-c1ccc(F)cc1

InChI Key InChIKey=MARDRTGXZRXTIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288239   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288239(5-(6-(4-Fluorophenyl)-2-(trifluoromethyl)-[1,2,4]t...)
Affinity DataIC50:  0.0630nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent