BDBM288243 2-Ethyl-6-(4-fluorophenyl)-5-(7-methyl-1H-indazol-5-yl)-::US10087185, Example 61

SMILES CCc1nc2ccc(-c3ccc(F)cc3)c(-c3cc(C)c4[nH]ncc4c3)n2n1

InChI Key InChIKey=TVMWZRZTIRIKQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288243   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288243(2-Ethyl-6-(4-fluorophenyl)-5-(7-methyl-1H-indazol-...)
Affinity DataIC50:  0.200nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent