BDBM288616 US10087191, Example 21

SMILES CCn1cc(cn1)-c1ccc2[C@H](N(CC(C)(C)F)[C@H](C)Cc2c1)c1c(F)cc(\C=C\C(O)=O)cc1F

InChI Key InChIKey=DCTDERJCKOUJPR-YCCGHEQVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288616   

TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM288616(US10087191, Example 21)
Affinity DataIC50:  0.320nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent