BDBM288620 (E)-3-(4-((1S,3R/1R,3S)-6-(6-aminopyridin-3-yl)-2-(2-fluoro-2-methylpropyl)-3-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)-3,5-difluorophenyl)acrylic acid::US10087191, Example 27
SMILES CC1Cc2cc(ccc2C(N1CC(C)(C)F)c1c(F)cc(\C=C\C(O)=O)cc1F)-c1ccc(N)nc1
InChI Key InChIKey=XNCJSQPFRGECJM-RUDMXATFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288620
Affinity DataIC50: 19.8nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair