BDBM288621 (E)-3-(3,5-difluoro-4-((1S,3R/1R,3 S)-2-(2-fluoro-2-methylpropyl)-3-methyl-6-(pyridin-3-yl)-1,2,3,4-tetrahydroisoquinolin-1-yl)phenyl)acrylic acid::US10087191, Example 28
SMILES CC1Cc2cc(ccc2C(N1CC(C)(C)F)c1c(F)cc(\C=C\C(O)=O)cc1F)-c1cccnc1
InChI Key InChIKey=PZIJVZDKKQUGLE-RMKNXTFCSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288621
Affinity DataIC50: 2.28nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair